1. Which among the following hormone can be used as a drug to treat cardiac arrest ?





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MCQ->Which among the following hormone can be used as a drug to treat cardiac arrest ?....
MCQ-> Read the following case – let and answer the question that follow Krishna Reddy was the head of a pharmaceutical company that was trying to develop a new product. Reddy, along with his friend Prabhakar Rao, assessed that such products had mixed success. Reddy and Rao realized that if a new product (a drug) was a success, it may result in sales of 100 crores but if it is unsuccessful, the sales may be only 20 crores. They further assessed that a new drug was likely to be successful 50% of times. Cost of launching the new drug was likely to be 50 crores. Now, Reddy and Rao were in a quandary whether the company should go ahead and market the drug. They contacted Raj Adduri, a common friend for advice. Adduri was of the opinion that given the risky nature of launch, it may be a better idea to test the market. Rao and Reddy realized test marketing would cost 10 crores. Adduri told them the previous test marketing results have been favorable 70% of times and success rate of products favorably tested was 80%.Further, when test marketing results were unfavorable; the products have been successful 30% of the times.How much profit can the company expect to earn if it launches the new drug(suppose there are no additional costs)?
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MCQ-> Throughout human history the leading causes of death have been infection and trauma, Modem medicine has scored significant victories against both, and the major causes of ill health and death are now the chronic degenerative diseases, such as coronary artery disease, arthritis, osteoporosis, Alzheimer’s, macular degeneration, cataract and cancer. These have a long latency period before symptoms appear and a diagnosis is made. It follows that the majority of apparently healthy people are pre-ill.But are these conditions inevitably degenerative? A truly preventive medicine that focused on the pre-ill, analyzing the metabolic errors which lead to clinical illness, might be able to correct them before the first symptom. Genetic risk factors are known for all the chronic degenerative diseases, and are important to the individuals who possess them. At the population level, however, migration studies confirm that these illnesses are linked for the most part to lifestyle factors — exercise, smoking and nutrition. Nutrition is the easiest of these to change, and the most versatile tool for affecting the metabolic changes needed to tilt the balance away from disease.Many national surveys reveal that malnutrition is common in developed countries. This is not the calorie and/or micronutrient deficiency associated with developing nations (type A malnutrition); but multiple micronutrient depletion, usually combined with calorific balance or excess (Type B malnutrition). The incidence and severity of Type B malnutrition will be shown to be worse if newer micronutrient groups such as the essential fatty acids, xanthophylls and falconoid are included in the surveys. Commonly ingested levels of these micronutrients seem to be far too low in many developed countries.There is now considerable evidence that Type B malnutrition is a major cause of chronic degenerative diseases. If this is the case, then t is logical to treat such diseases not with drugs but with multiple micronutrient repletion, or pharmaco-nutrition’. This can take the form of pills and capsules — ‘nutraceuticals’, or food formats known as ‘functional foods’, This approach has been neglected hitherto because it is relatively unprofitable for drug companies — the products are hard to patent — and it is a strategy which does not sit easily with modem medical interventionism. Over the last 100 years, the drug industry has invested huge sums in developing a range of subtle and powerful drugs to treat the many diseases we are subject to. Medical training is couched in pharmaceutical terms and this approach has provided us with an exceptional range of therapeutic tools in the treatment of disease and in acute medical emergencies. However, the pharmaceutical model has also created an unhealthy dependency culture, in which relatively few of us accept responsibility for maintaining our own health. Instead, we have handed over this responsibility to health professionals who know very little about health maintenance, or disease prevention.One problem for supporters of this argument is lack of the right kind of hard evidence. We have a wealth of epidemiological data linking dietary factors to health profiles/ disease risks, and a great deal of information on mechanism: how food factors interact with our biochemistry. But almost all intervention studies with micronutrients, with the notable exception of the omega 3 fatty acids, have so far produced conflicting or negative results. In other words, our science appears to have no predictive value. Does this invalidate the science? Or are we simply asking the wrong questions?Based on pharmaceutical thinking, most intervention studies have attempted to measure the impact of a single micronutrient on the incidence of disease. The classical approach says that if you give a compound formula to test subjects and obtain positive results, you cannot know which ingredient is exerting the benefit, so you must test each ingredient individually. But in the field of nutrition, this does not work. Each intervention on its own will hardly make enough difference to be measured. The best therapeutic response must therefore combine micronutrients to normalise our internal physiology. So do we need to analyse each individual’s nutritional status and then tailor a formula specifically for him or her? While we do not have the resources to analyze millions of individual cases, there is no need to do so. The vast majority of people are consuming suboptimal amounts of most micronutrients, and most of the micronutrients concerned are very safe. Accordingly, a comprehensive and universal program of micronutrient support is probably the most cost-effective and safest way of improving the general health of the nation.The author recommends micronutrient-repletion for large-scale treatment of chronic degenerative diseases because
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MCQ-> Read the passage carefully and choose the best answer to each question out of the four alternatives.Bertrand Russell in The Conquest of Happiness has said that the sole reason of unhappiness finding refuge in the heart of man is the unhindered growth of “self- centred passions”. These passions are more often materialistic. And in the pursuit of materialistic passions, man becomes alienated from the society. Failure in his pursuit often leads him to discontentment and dejection and he finds himself a misfit in this world. In the modern world, none is unaffected by stress. The stress to outdo the other in this mad rat race of consumerism often leads to depression.Even children are not spared from this. They are supposed to fare better than their classmates in examinations and other co-curricular activities. So man, right from childhood, has to face the brunt of being born in this fast changing society. A section of the youth, unable to cope with the expectations of their loved ones, either end their lives or experiment with drugs, for seeking temporary mental relaxation provided by the initial intake, encourages people to indulge in them more often. The body then becomes totally dependent on drugs and cannot survive without the daily dose. With regular intake the amount required to produce the effect also increases. This physical and mental dependence on drugs is called drug addiction. Drug addiction is a psychiatric, psychological and social problem. While persons of all ages and at all places are open to drug use the most susceptible among them are the youth. It has attained the proportions of almost an epidemic among the youth. It is mostly introduced to an unsuspecting person by his friends and is usually observed that once addicted to drugs, they initiate others to drugs. Some youngsters take to drugs because they are poked fun as if they do not use drugs. And some take drugs just to seek company or break boredom. In addition to these, other factors that lead to drug addiction are — lack of parental care and supervision, lack of moral and religious education, media and pop culture, broken homes, hatred for any authority, etc. Seeking refuge in drugs relieves tensions, eases depressions and removes inhibitions, although the period of ecstasy is apparently short-lived. Which of the following statements is true ?
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