1. Father of gene therapy

Answer: Anderson

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MCQ-> Analyse the following passage and provide appropriate answers for questions that follow. Certain variants of key behavioural genes, “risk allele” make people more vulnerable to certain mood, psychiatric, or personality disorders. An allele is any of the variants of a gene that takes more than one form. A risk allele, then, is simply a gene variant that increases your likelihood of developing a problem. Researchers have identified a dozen - odd gene variants that can increase a person’s susceptibility to depression, anxiety and antisocial, sociopathic, or violent behaviours, and other problems - if, and only if, the person carrying the variant suffers a traumatic or stressful childhood or faces particularly trying experiences later in life. This hypothesis, often called the “stress diathesis” or “genetic vulnerability” model, has come to saturate psychiatry and behavioural science. Recently, however, an alternate hypothesis has emerged from this one and is turning it inside out. This new model suggests that it’s a mistake to understand these “risk” genes only as liabilities. According to this new thinking, these “bad genes” can create dysfunctions in unfavourable contexts - but they can also enhance function in favourable contexts. The genetic sensitivities to negative experience that the vulnerability hypothesis has identified, it follows, are just the downside of a bigger phenomenon: a heightened genetic sensitivity to all experience. This hypothesis has been anticipated by Swedish folk wisdom which has long spoken of “dandelion” children. These dandelion children - equivalent to our “normal” or “healthy” children, with “resilient” genes - do pretty well almost anywhere, whether raised in the equivalent of a sidewalk crack or well - tended garden. There are also “orchid” children, who will wilt if ignored or maltreated but bloom spectacularly with greenhouse care. According to this orchid hypothesis, risk becomes possibility; vulnerability becomes plasticity and responsiveness. Gene variants generally considered misfortunes can instead now be understood as highly leveraged evolutionary bets, with both high risks and high potential rewards. In this view, having both dandelion and orchid kids greatly raises a family’s (and a species’) chance of succeeding, over time and in any given environment. The behavioural diversity provided by these two different types of temperament also supplies precisely what a smart, strong species needs if it is to spread across and dominate a changing world. The many dandelions in a population provide an underlying stability. The less - numerous orchids, meanwhile, may falter in some environments but can excel in those that suit them. And even when they lead troubled early lives, some of the resulting heightened responses to adversity that can be problematic in everyday life - increased novelty - seeking, restlessness of attention, elevated risk - taking, or aggression - can prove advantageous in certain challenging situations: wars, social strife of many kinds, and migrations to new environments. Together, the steady dandelions and the mercurial orchids offer an adaptive flexibility that neither can provide alone. Together, they open a path to otherwise unreachable individual and collective achievements.The passage suggests ‘orchids’:
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MCQ->The five sentences labelled (1, 2, 3, 4, 5) given in this question, when properly sequenced, form a coherent paragraph. Each sentence is labelled with a number. Decide on the proper order for the sentences and key in this sequence of five numbers as your answer.1. Scientists have for the first time managed to edit genes in a human embryo to repair a genetic mutation, fuelling hopes that such procedures may one day be available outside laboratory conditions. 2. The cardiac disease causes sudden death in otherwise healthy young athletes and affects about one in 500 people overall. 3. Correcting the mutation in the gene would not only ensure that the child is healthy but also prevents transmission of the mutation to future generations. 4. It is caused by a mutation in a particular gene and a child will suffer from the condition even if it inherits only one copy of the mutated gene. 5. In results announced in Nature this week, scientists fixed a mutation that thickens the heart muscle, a condition called hypertrophic cardiomyopathy....
MCQ->A father and his son are waiting at a bus stop in the evening. There is a lamp post behind them. The lamp post, the father and his son stand on the same straight line. The father observes that the shadows of his head and his son's head are incident at the same point on the ground. If the heights of the lamp post, the father and his son are 6 metres, 1.8 metres and 0.9 metres respectively, and the father is standing 2.1 metres away from the post then how far (in metres) is son standing form his father?...
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MCQ-> On the basis of the information provided, answer the questions below.Eight doctors P, Q, R, S, T, U, V and W of the same family i.e. father, mother, father’s sister, mother’s brother, 2 daughters and 2 sons visit a clinic every day for one hour each except on Monday which is a holiday. The timings are 9 am to 1 pm and 2 pm to 6 pm, with lunch time from 1 pm to 2 pm. Each has a different specialisation namely Cardiologist, Orthodontist, Neurologist, Paediatrician, Gynaecologist, Urologist, Radiologist and General Physician.1.No doctor visits the clinic before doctor Q and after doctor U. 2.The Orthodontist visits right after lunch and is followed by R who is a female. 3.The mother comes in at the same place before lunch as the younger son P after lunch. 4.The General Physician is the sister of Urologist’s father and is last to visit before lunch. 5.The Cardiologist is the first while the elder daughter is the last to visit. 6.T is the mother’s brother of U and visits between the father and mother. 7.Before 1 pm, V comes after the Radiologist, who is second to visit during the day 8.S, the mother comes at 11 am after the father. 9.The Neurologist is at the same place after lunch as the Gynaecologist before lunch and comes right after Urologist.The General Physician is a ____________ and comes at ___________
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