Middle number = (Difference between the numbers written on left hand side)*(Sum of the numbers written on right hand side) 80 = (15 - 5)*(2 + 6) 65 = (9 - 4)*(7 + 6) Therefore, ? = (13 - 11)*(16 + 8) = 2*24 = 48. Hence, option B is the correct answer.
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