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You Are On Multi Choice Question Bank SET 1781
89051. Which of the following is predominantly proteolytic?
(A): C. sporogenes (B): C. histolyticum (C): Both and (D): C. speticum
89052. Which of the following properties are the characteristics of tetanospasmin?
(A): It is a heat-labile protein (B): It is a neurotoxin (C): It can be toxoided (D): All of these
89053. Types of exotoxin, most commonly associated with botulism in man, is/are?
(A): Type A (B): Type B (C): Type E (D): All of these
89054. Nagler's reaction is useful for the identification of
(A): C tetani (B): C perfringens (C): C botulinum (D): C difficile
89055. The deflection angle may have any value between
(A): 0 and 180 (B): 0 and 90 (C): 0 and 120 (D): 0 and 45
89056. A line normal to the plump line at all points is known as:
(A): Horizontal line (B): Vertical line (C): Line of collimation (D): Level line
89057. The best wood for sleeper is:
(A): Sal (B): Teak (C): Deodar (D): Chirr
89058. An imaginary line lying through out the surface of the ground and preserving an constant inclination to the horizontal is known as
(A): Counter line (B): Counter interval (C): Horizontal equivalent (D): Countour gradient
89059. Plaster of parts is obtained from the clacinations of:
(A): Bauxite (B): Limestone (C): Dolomite (D): Gypsum
89060. Which of the following statements on replication in E.coli is correct?
(A): It occurs in a unidirectional manner (B): It occurs in bidirectional manner (C): Always uses T7 DNA polymerase when infected by T7 phage (D): Occurs only when λ phase has infected E. coli
89061. The replication of chromosomes by eukaryotes occurs in a relatively short period of time because
(A): the eukaryotes have more amount of DNA for replication (B): the eukaryotic replication machinery is 1000 times faster than the prokaryotes (C): each chromosome contains multiple replicons (D): eukaryotic DNA is always single stranded
89062. In E.coli, which enzyme synthesizes the RNA primer for Okazaki fragments?
(A): DnaA (B): DnaC (C): DnaG (D): all of these
89063. During which of the following process a new copy of a DNA molecule is precisely synthesized?
(A): Trasformation (B): Transcription (C): Translation (D): Replication
89064. DNA gyrase is inhibited by
(A): tetracycline (B): nalidixic acid (C): both and (D): cephalosporin
89065. Which of the following enzymes unwind short stretches of DNA helix immediately ahead of a replication fork?
(A): DNA polymerases (B): Helicases (C): Single-stranded binding proteins (D): Topoisomerases
89066. During DNA replication in prokaryotes, synthesis begins on the circular chromosome
(A): always at the same place (B): at any stretch of DNA that is high in AT pairs (C): randomly on the chromosome (D): at the promoter
89067. DNA replication rates in prokaryotes are approximately of the order of
(A): 10 bases per second (B): 1,00 bases per second (C): 1,000 bases per second (D): 10,000 bases per second
89068. Which of the following lacks 3'-5' exonuclease activity?
(A): Short fragment of DNA polymerase I (B): Taq DNA polymerase (C): T4 DNA ligase (D): All of the above
89069. Both strands of DNA serve as templates concurrently in
(A): replication (B): excision repair (C): mismatch repair (D): none of these
89070. Proofreading activity to maintain the fidelity of DNA synthesis
(A): occurs after the synthesis has been completed (B): requires the presence of an enzyme separate from the DNA polymerases (C): occurs in prokaryotes but not eukaryotes
89071. Which of the following repairs nicked DNA by forming a phosphodiester bond between adjacent nucleotides?
(A): Helicase (B): DNA gyrase (C): Topoisomerases (D): DNA ligase
89072. The enzyme that catalyzes the synthesis of DNA is called
(A): DNA polymerase (B): DNA gyrase (C): DNA ligase (D): helicase
89073. Which of the following possesses both 5'-3' and 3'-5' exonuclease activity?
(A): Kornberg enzyme (B): DNA polymerase III (C): Taq DNA polymerase (D): None of these
89074. A pattern of dots that appears on AutoCAD screen of computer but that does not called:
(A): Snap (B): Ortho (C): Grid (D): Limits
89075. A pipe used to carry discharge from sanitary fittings like bath rooms,Kitchens et
(A): Soil pipe (B): Waste pipe (C): Vent pipe (D): Anti siphon age pipe
89076. The part of circle bounded by an arc and its chord is known as
(A): Semi circle (B): Chord (C): Segment (D): Sector
89077. A couple close roof is used for span upto
(A): 3.5 m (B): 5 m (C): 9 m (D): 14 m
89078. The process of hardening the concrete mixes by keeping its surface moist for a certain period is called:
(A): Floating (B): Curing (C): Screeding (D): None of these
89079. What was the first eukaryotic chromosome to be sequenced?
(A): Yeast chromosome III (B): Yeast chromosome XI (C): Arabidopsis chromosome IV (D): None of these
89080. Which of the following mutations arise without exposure to external agents?
(A): Spontaneous mutations (B): Analogous mutations (C): Induced mutations (D): None of these
89081. Due to which of the following DNA repair mechanisms, one is able to distinguish newly synthesized DNA strands from older one?
(A): New strands do not contain cytosine bases (B): New strands are lower in molecular size (C): Old strands are methylated while new strands are not (D): New strands are methylated while old strands are not
89082. Which of the following bacterial genome was sequenced first?
(A): E. coli (B): S. pneumoniae (C): H. influenzae (D): S. thermophilus
89083. A nonsense mutation may result into
(A): an abnormal elongation of a polypeptide (B): a large deletion within the reading frame of a gene (C): a premature termination of the synthesis of a polypeptide (D): modification of mRNA
89084. Which of the following mutation affects only a single nucleotide?
(A): Aerial mutation (B): Site mutation (C): Point mutation (D): Regional mutation
89085. When mutations involve vital functions so that the mutants are nonviable, it is a
(A): nonsense mutation (B): lethal mutation (C): transversion (D): none of these
89086. A mutagen is defined as
(A): an enzyme that repairs mutations (B): a chemical or physical agent that induces mutations (C): an inhibitor of gene modification (D): a molecule which stabilizes DNA thus prevents mutations from occurring
89087. The DNA sequences of rRNA genes can be used to
(A): assess relatedness of eukaryotes but not prokaryotes (B): obtain a tentative identification of a new microorganism (C): predict the pulsed field gel pattern of a microorganism (D): predict whether a bacteria will be gram-positive or gram-negative
89088. A nonsense mutation introduced into the DNA sequence of a gene may
(A): cause premature termination of the mRNA (B): shorten the length of the protein encoded by the gene (C): have no effect on the transcript or protein made (D): cause a shift in reading frame
89089. Which of these mechanisms for thymine dimers repair lead to mutations?
(A): Excision repair (B): Photoreactivation (C): SOS repair (D): Never leads to mutation
89090. Frame shift mutation may occur as a result of
(A): formation of a thymine-dimer (B): deamination of cytosine to uracil (C): conversion of guanine to xanthine (D): none of the above
89091. Thymine dimers are directly repaired with the help of visible light by process known as
(A): phosphorylation (B): excision repair (C): photosynthesis (D): photoreactivation
89092. The promoter on an expression vector used to overproduce proteins in bacteria is
(A): a bacterial promoter (B): expressed both in bacteria and mammalian cells (C): not a regulated promoter (D): the natural promoter of the gene being cloned
89093. Differentiation of four different bases in automated sequencing systems is that each base has
(A): different radioactive tag (B): cytosine at start (C): unique antibody bound to it (D): distinctive fluorescent tag
89094. Genetic variations are
(A): temporary (B): influenced by the environment (C): stable (D): not heritable
89095. The mutation which will not affect the length of a protein is,
(A): nonsense mutation (B): missense mutation (C): frameshift mutation (D): all of these
89096. Changes in which of the following characterizes mutations?
(A): Phenotype (B): Genotype (C): Both and (D): None of these
89097. Which of the following(s) is/are steps in excision repair mechanisms?
(A): Excision (B): Incision (C): Ligation (D): All of these
89098. The whole-genome shotgun sequencing approach depends primarily on
(A): rapidly sequencing thousands of small randomly cloned fragments (B): methodical sequencing a few large cloned fragments of DNA (C): sequencing the bacterial chromosome while it is still intact (D): all of the above
89099. The lime commonly used under damp situation is
(A): Fat lime (B): Hydraulic lime (C): Lean lime (D): Hydrated lime
89100. The slope of the road pavement in the longitudinal direction is called:
(A): Alignment (B): Gradient (C): Supper elevation (D): Length of summit
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