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You Are On Multi Choice Question Bank SET 1775
88751. Which is not a function of IgG?
(A): Major antibody in serum (B): First antibody type produced against an antigen during the primary antibody response (C): Activates or fixes complement (D): Involved in opsonization
88752. J chain is present in
(A): IgA (B): IgM (C): Both and (D): IgE
88753. Heat-labile class of immunoglobulins include
(A): IgA (B): IgE (C): IgG (D): IgM
88754. Which of the following (s) is/are function (s) of Fc fragment of IgG?
(A): It determines catabolic rate (B): It binds complement (C): It is related to passage of IgG across the placental barrier (D): All of these
88755. Which of the following is the phylogenetically oldest immunoglobulin?
(A): IgE (B): IgM (C): IgG (D): All are similar
88756. The secretary component of sIgA is
(A): made by plasma cells that secrete dimeric IgA (B): added to dimeric IgA by the M cell (C): formed by cleavage of an epithelial cell receptor used to transport the dimeric IgA across the epithelial cell (D): made by T cells
88757. Anti-Rh antibodies are
(A): IgG type (B): IgA type (C): IgE type (D): IgD type
88758. Which is not a function of IgA?
(A): Protect mucosal surfaces (B): Fix complement (C): Protect eyes (D): Agglutinate antigen
88759. The class of immunoglobulins which can cross the placenta is
(A): IgM (B): IgG (C): IgA (D): IgD
88760. Self reactive antibodies are not found in significant concentration in normal serum because
(A): it is impossible to generate a self-reactive antibody (B): self reactive B cells are killed by CD8 T cells (C): B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide (D): self reactive B cells switch to IgA which is all secreted and not present in serum
88761. Simulation of which of the following will lead to appearance of first antibody to appear following stimulation by an antigen?
(A): IgM (B): IgA (C): IgE (D): IgG
88762. Antigen binding sites of an immunoglobulin are located in
(A): light chain alone (B): heavy chain alone (C): Fc region of the antibody (D): Fab regions of the antibody
88763. Which of the following mediates Type I hypersensitivity reaction?
(A): IgE (B): IgG (C): IgM (D): IgD
88764. Ring test is used for
(A): C-reactive protein test (B): typing of streptococci and pneumococci (C): all of the above
88765. Precipitation reaction can be converted into agglutination reaction by coating soluble antigen onto
(A): bentonite particles (B): RBCs (C): latex particles (D): all of these
88766. Commercially available ELISA kits are used for the detection of
(A): rotavirus (B): hepatitis B surface antigen (C): anti-HIV antibodies (D): all of these
88767. Monoclonal antibody production requires
(A): mouse splenic lymphocytes (B): mouse myeloma cells (C): both and (D): none of these
88768. Quellung reaction is used for typing of
(A): Klebsiella pneumoniae (B): Streptococcus pneumoniae (C): Both and (D): None of these
88769. Fluorescent treponemal antibody test is an example of
(A): indirect immunofluorescence (B): direct immunofluorescence (C): both and (D): none of these
88770. Counter-immunoelectrophoresis is used for the detection of
(A): Meningococcal antigen (B): Hepatitis B surface antigen (C): Alpha-fetoprotein (D): All of these
88771. The test (s) based on the principle of toxin neutralization is/are
(A): Schick test (B): both and (C): none of these
88772. Slide agglutination reaction is/are useful for the identification of the culture(s) of
(A): Shigella (B): Vibrio cholerae (C): Salmonella (D): All of these
88773. Amount of various immunoglobulin classes can be measured by
(A): double diffusion in one dimension (B): single diffusion in two dimensions (C): single diffusion in one dimension (D): double diffusion in two dimensions
88774. VDRL test is an example of
(A): Tube test (B): Ring test (C): Slide test (D): none of these
88775. Weil-Felix reaction is based on sharing of antigens between
(A): sheep RBCs and EB virus (B): mycoplasma and human O group RBCs (C): rickettsial antigens and antigens of certain strains of Proteus (D): none of these
88776. Agglutination reaction is more sensitive than precipitation for the detection of
(A): antigens (B): antibodies (C): complement (D): antigen-antibody complexes
88777. Precipitation reaction is relatively less sensitive for the detection of
(A): antigens (B): antigen-antibody complexes (C): antibodies (D): complement
88778. In which of the following case a large lattice is formed?
(A): Antibody is in excess (B): Antigens and antibodies are in optimal proportion (C): Antigen is in excess (D): None of these
88779. Quick lime is a
(A): Product left immediately after the calcinations of pure lime stone (B): Carbonate of lime (C): Oxide of lime (D): Lime quickly treated with water
88780. A good quality cement should have higher percentage of:
(A): Silica (B): Free lime (C): Di calcium silicate (D): Tri calcium silicate
88781. Chemotherapeutic agents must
(A): prevent/destroy the activity of a parasite (B): be able to come in contact with the parasite by penetrating the cells (C): all of the above
88782. Novobiocin can be used against
(A): gram +ve Staphylococci (B): gram -ve Meningococci & Gonococci (C): Haemophilus (D): all of these
88783. Interference mechanism of ciprofloxacin and norfloxacin is due to their action on
(A): cell wall synthesis (B): cell membrane function (C): DNA function (D): protein synthesis
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